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Old Thu Mar 6, 2014, 05:05 AM
Mseth Mseth is offline
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Join Date: Sep 2013
Location: New Delhi, India
Posts: 186
jhasc

Quote:
Originally Posted by jhasc View Post
Hi
My Grand Father is suffering from This disease MDS-RAEB1 after doing Bone marrow doctor .The chemo was done ECITABINE/DECITEX(LYOPHILIZED) with this Medicine and this was given for 4 month . He Got Recovered and Both the Hemoglobin and Platelet recovered .After Completion of Medicine ,Again the bone marrow was done to test the actual condition reports shows the Positive effect .But again after 2 Month He has came to same condition and his health is deteriorating . Present his platelet is 40k and Hemo is 4. Please Advice Me what to do?? shall we do the chemo again or can we try something else? He is at age of 75
Present Platelet count on 5-3-2014
RBC:4.8
WBC:14700
Platelet:30k
Hello jhasc,

Sorry that your grandfather has this problem. You mention Hemo of 4 and then RBC of 4.8. RBC of 4.8 is good, but hemo of 4 is very low. If he has low hemoglobin and platelets he should be getting a transfusion with pRBC and platelet while you decide what other treatment to follow. For low WBC, injection Neupogen can be tried.
I do not have much direct knowledge but as I understand, internationally Vidaza and Decitabine are two options, but in India we have only the Decitabine option. Also, as far as I know, Decitabine is given every month, it cannot be discontinued. Did they discontinue after 4 months? Transplant is not an option at his age in India. What do the doctors suggest?
You can also start a new thread with your questions.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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