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Old Sat Aug 14, 2010, 05:42 AM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Nplate and Promacta

Hi McGill,
Yes, Promacta has always been behind Nplate and they started trials with MDS patients much earlier with Nplate. These studies showed increased blast cells in about 20% of the patients - most patients recovered when they didn't continue with Nplate. That is why FDA has a very serious warning about Nplate for MDS patients. FDA has a warning about Promacta for MDS patients too but we really don't know much about the effect in MDS patients.

Remember that 2 members of this forum have transformed to AML after taking Promacta - one within 1 month and the other after several months.

Next week, when I do blood work at the hospital, I will go to their library and get the article written by Mavroudi et al from Greece in Leuk Res. Then I will tell you more about the study.
Kind regards
Birgitta-A
Thalidomide 50 mg 5 caps/week since June 2010. Last platelet count 55.
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