Quote:
Originally Posted by Birgitta-A
Four weeks after I started to take Thalidomide my platelets increased to 43 from 22 and now after 6 months they are between 70 and 80.
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That sounds wonderful. How long do you think will Thalidomide work? Are there any studies?
Quote:
Originally Posted by Birgitta-A
As far as I have understood they looked for both increased fibrosis and blast cells during the trials with Nplate and in several cases the blast cells decreased when Nplate was stopped.
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Is it really proved that they looked also for increased fibrosis during the trials with Nplate/MDS? As there is nothing mentioned in the study reports we cannot be sure..
As i remember this decreasing of blasts happenend after cessation of Nplate only after a short intake-period and nobody knows if this reversible-effect would also work after blast encreasing after a longer period of NPlate.
I wonder how it could happen that there was a such rapid, high blast encreasing with the two MDS patients who transformed into AML without (any?) notice of the study-management. Could these transformations have been prevented during the period the blasts were increasing?
Also it seems quite strange that blasts in MDs go back after the cessation of a medication. Did you hear from such a fact earlier?
Regards,
Margarete