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Old Thu Jun 17, 2010, 05:03 AM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
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Vidaza

Hi Chirley,
Good that you manage with so low WBCs and that your platelets are OK!

It's not common that you get a positive response after one cycle as you already know - that is why the effects of drug is evaluated after 6 months.

In this article they write: “The time to response data indicate that azacitidine can have an effect at the bone marrow level as early as the first treatment cycle. However, for this effect to translate into an improvement in bone marrow function leading to clinically significant increases in peripheral cell counts, the majority of responders can require up to six cycles of azacitidine.”
http://www.jcojournal.org/cgi/content/full/24/24/3895
Kind regards
Birgitta-A
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