Hi Dan,
Your counts are really very good except for the platelets. As you know almost all drugs can decrease platelets.
Vidaza has showed quite positive results in several studies of patients with trisomy 8 but all groups are small and need confirmation:
https://ash.confex.com/ash/2009/webp...aper23003.html
You seem to know much about fibrosis already. I have not been able to find any studies about the impact of for example Vidaza on regression of fibrosis but here is an abstract about response to Vidaza in patients with MDS with marrow fibrosis. The overall response rate was 63% that is quite good compared with other patient groups.
http://meeting.ascopubs.org/cgi/cont.../18_suppl/7089
Kind regards
Birgitta-A