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Old Sun May 15, 2011, 05:45 AM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Promacta

Hi Sally,
You are right about the concern about the risk for fibrosis - they have now started the third trial for MDS patients and the second for AA patients.

I suppose Don is in this trial: http://clinicaltrials.gov/ct2/show/N...pag+mds&rank=2

You know when the two new drugs for low platelets were approved I was hoping that they would soon be in trials for MDS because they were in trials for several other diseases with low platelets due to chemo like Hepatitis C. Then I was scared because of the reports about increased fibrosis and blasts after treatment with Nplate. At that time I wrote that platelet transfusions were safer though I know that most patients won't have a good effect after many platelet transfusions. Now I have changed my mind again - perhaps Promacta will be a good drug for MDS patients.

Hope Don will have a positive response!
Kind regards
Birgitta-A
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