Hi Roger,
You know Vidaza with a little more than 50% improvment is the best drug for most MDS patients.
There is only one other drug approved for MDS patients without the 5q- chromosome aberration:
Dacogen (decitabine) 17% improved.
http://www.medilexicon.com/drugs/dacogen.php
Then some patients (one member of Marrowforums) have good results with
Epival (valproic acid) 44% improved.
http://bloodjournal.hematologylibrar...ull/104/5/1266
Some patients without the 5q- chromosome aberration respond to
Revlimid (lenalidomide) 43% improved.
http://bloodjournal.hematologylibrar...tract/111/1/86
The patient groups in these studies are different - some have a more advanced disease so the results can not really be compared. I post the links so you could read something about the drugs.
Kind regards
Birgitta-A