[teo]

Hi All,

I need some advice on the above drug combinations (Danazol 200mg*2 + cyclosporine 25mg*4) as i am a bit worry on the combine dosage. Just wondering has anyone try these combinations before.

Some info why the trainee Hema wants my mum to try the combine dosage. My mum has been on Danazol for around 18 months (started Nov 2013), after consuming the Danazol for around 8/9 months, the HGB has been progressing quite well. The HGB has increased from 8 plus to 11.4 in around 6 months (Sept 2014 till Feb 2015), but the HGB drops slowly after the hospital changed the Danazol supplier, Different Supplier from Feb 2015. From Feb 2015 till now, the HGB drop from 11.4 to 9.

I suspect the main reason might be the "NEW danazol" as the timing is exactly matched. Just wondering anyone know about the contains of the Danazol, i mean the drugs portion used in making the drug itself.

As the HGB dropped, the trainee hema recommending the combine drugs but also telling my sis that there might be adverse side effect.

Any comments is welcome and appreciated. Thanks in advance.

Medical History
Actually my mum tried cyclosporine before with the dosage from 75mg/day to 150mg/day within 6 months period few years back, no response.