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From my Monica Bessler talk...
From what I understand...
PNH affects both whites and reds.
However, your red cells are what get ripped to shreds by your immune system. This makes them impossible to test for how profound your PNH is.
The whites are used for testing purposes because they don't get torn asunder like the red cells, although they do suffer from that missing protein. So, they serve as a PNH measuring stick, but it's the red cells that create the clinical issues. The clotting risk is not yet entirely understood.
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Ryan Jay: 38-yo, dx SAA: 7/25/10, ATG: 8/10/10. CR with counts still rising. HGB: 13, Plt: 137 WBC 5.1 ANC
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