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Old Wed May 19, 2010, 11:07 PM
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Join Date: Mar 2009
Posts: 193
Appt Today 5/19/2010 (Wed)

Today Ron's WBCs were increased to 2.3 but the overall calculation (Manual DIF - Differential) was less than the required 500 count to recieve chemo today (According to clinical trial rules). We asked the Doctor if Ron had been "off the clinical trial today" would he have received chemo (Vidaza)?

Our doctor answered that he would not recommend receiving Vidaza right now, even if not on the clinical trial. He told us not to become over anxious and not to get "in a hurry" about making any decisions right now, due to Ron's current condition.

Ron feels good, he has lots of energy, and isn't run down at all right now. Today his HGB was 13.7, matter of fact, all counts looked good, although I like the WBCs to be higher. They said Ron's WBCs show progress that they are coming back up with the delay of treatment.

What Next? Next Wed, we will return to the clinic and discuss situation. If WBCs (Manual-DIF counts) allow Vidaza, then, Ron will be able to continue on clinical trial (According to today's report of what the clinical trial allows). Initially, we thought Ron was automatically off the trial if Vidaza delayed another week.

The doctor assured us he would not recommend anything that he believes would be detrimental to Ron's health. Ron's due a BMB in the next 4-6 weeks, regardless if he's on or off clinical trial, so, we'll be able to see how the marrow is behaving.

We felt today was a very encouraging appt, because, the Doctor is not worried. He assured us that this reaction to Vidaza is common (the norm), and that, when this happens, the body needs a break.

I will update all next week.
God Bless all of You, Cindy
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Cindy, wife of Ron 66 dx w/MDS(RARS)Feb'09,Vidaza 13mons. BMB 2/10 -5q/increased blasts. Watch/wait May-Jul10. Revlimid Jul-Aug10:A-Fib. BMB Aug18, 12%blasts. MDS to AML. Induction completed 9/21/10. BMB Oct10:CR. Consolidaton:10/25/10. Dacogen Dec27-29. SCT on Hold. Fevers/Nt sweats Jan11.
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