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Melleejohn,
I have to go with the 10/10 match if it is available. Johns Hopkins has been a pioneer with the 5/10 haploid approach and has been successful. They use a alot more immune suppression to help with the rejection concerns. In general, the less the match, the higher the risk of gvhd and its related side effects.
As Ray says, go with what the doctors recommend. I had a 10/10 MUD in February of 2014. GVHD has been lower grade and manageable from day one.
Dan
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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