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Old Thu Aug 20, 2015, 10:10 PM
evansmom evansmom is offline
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Join Date: Nov 2007
Location: Ontario, Canada
Posts: 203
I'll third that notion...If it were myself or my son (who had a successful 9/10 MUD BMT), I'd definitely push for an 8/10, 9/10 or 10/10 unrelated donor. Depending on where the mismatches are, a slightly imperfect match can be very successful. It's a very fine line indeed between successful transplant, graft failure and graft versus host. I'm not sure however if a bit of GVH is desired the same way it is in treating leukemia with a graft versus leukemia effect. That would be a good question to ask the team.

At any rate, your husband will be in very good hands at JH, but please realize that there certainly is considerably more risk of serious complications with one of the kids being the donor (haploid transplant).

Best wishes.
__________________
Nicole, mom to Evan (20); diagnosed SAA November 2007, hATG mid-November 2007, no response after 6 months, unrelated 9/10 BMT June 2008, no GVH, health completely restored thanks to our beloved donor Bryan from Tennessee.

www.caringbridge.org/visit/evanmacneil
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