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I was told that it is perceived that the risk of serious reactions during the administration of the ATG (i.e. anaphylaxis shock) was greater if the same serum was repeated. That is why they alternate horse-rabbit. There hasn't been a clinical trial to prove or disprove this, but it is the perception.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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