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Nplate or Promacta
Hi Margarete,
You know there are two drugs that stimulate the fabrication of platelets - Nplate and Promacta. Nplate was approved a little before Promacta. They started trials with Nplate for MDS patients very early.
We still have not seen results from a single study with Promacta in MDS patients. We can hope that Promacta leads to less fibrosis and that the risk for increased blast cells is lower. What we know about Promacta is that they had to terminate a study with Promacta for hepatitis C patients with low platelets due to treatment with Interferon because the patients got too high liver tests.
At least 2 members of this forum have been treated with Promacta - I think both have developed leukemia. One member - Kirby - has continued Promacta treatment and is satisfied with the result.
Kind regards
Birgitta-A
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