You should be very concerned Paul.
In general, most MDS patients who regularly have PRBC transfusions begin a chelation therapy after 20 units infused or serum ferritin above 1000 ug/L. I highly recommend you discuss beginning a suitable chelation therapy ASAP with your doc.
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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%
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47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).