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Old Mon Apr 15, 2013, 09:42 PM
NLJabbari NLJabbari is offline
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Join Date: Aug 2006
Location: San Jose, California
Posts: 139
Hi Grifmat,

Re: Cyclosporine dose-generally when a patient is introduced to Cyclosporine, they are monitored to make sure the kidneys aren't being stressed-out. Not all brands of CsA's are bio-equivalent or processed in the same manner. Gengraf is the generic for Neoral and it has an increased bioavailability in comparison to Sandimmune. My son was recently switched from Sandimmune to Gengraf and his doctor ordered him not to eat 2 hours prior and 1 hour post his dosage. She said this would help absorb the med. best.

Again, I think your mom is taking a high enough dose that she should be monitored and more than likely should be taking magnesium. My son has to take 4 (Mag-Ox 400mg each) just to stay in the lower range of "Normal" Magnesium levels. He takes 2 w/lunch and 2 w/dinner.
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06/2004 my son was dx with SAA at the age of 10. No sibling BM match. He underwent ATG (H)/CsA. Relapsed 05/12 & dx'ed w/PNH. Currently in wait/see mode for Solaris as he is asymptomatic...
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