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Ray,
Depending on the dose of prednisone, you may have more white blood cells, specifically ANC, than normal as it is said to release reserves of white blood cells into the blood stream. As others have noted, it could also be caused by bacterial infection or some other cause. I know that when I was on prednisone years ago, my ANC jumped to almost 20k from 5k, but that was 100mg per day.
I may be off base, but my understanding is the following:
Tac - WBC neutral more or less
Pred - tends to increase WBC, but weakens their ability to do the job
Imbruvica - tends to reduce WBC
I am wondering if the timing of your blood test has been at a consistent point with your cycles of Imbruvica - meaning that you may be at a different stage of blood count recovery than the last couple of tests.
Dan
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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