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This is still fairly new research. The first any of us heard about it was in 2005, and then only related to AA. The thinking at that point was that people who had shortened telomeres were less likely to respond to IST (ATG/cyclo), so it might be better for them to go directly to transplant. That is the only practical application I can think of. The test is not routinely done, and we didn't ask for it because by that point we already knew that Ken had responded to IST. The relationship to relapse is news to me, as is the MDS connection.
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-Lisa, husband Ken age 60 dx SAA 7/04, dx hypo MDS 1/06 w/finding of trisomy 8; 2 ATGs, partial remission, still using cyclosporine
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