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Old Wed Nov 9, 2016, 11:20 PM
DanL DanL is offline
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Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Jacqui,

This is a really difficult biopsy result to interpret. The first appearance would be aplastic anemia or hypo-plastic mds, but could just as readily be something affiliated with the auto-immune liver disease. Anytime the marrow struggles, there is a possibility of generating dysplastic cells, which is one of the key criteria for MDS. Problem is that vitamin deficiencies may also cause some of these readings.

With the liver issues, I am not sure which treatments are applicable. Normally some form of immune suppression is utilized for aplastic anemia, and for hypo-mds. Bone marrow transplants are used as potential cures in both cases.

Prior to agreeing to any treatment though, I would suggest that a second opinion might be in order, especially if the doctors you are working with don't handle a lot of bone marrow failure diseases.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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