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Old Thu Dec 30, 2010, 08:16 AM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,406
John's ALP remained elevated for quite some time....years actually. Our doctors said it was because of the bone marrow. This enzyme is produced in the liver, kidneys, intestinal mucosa and bones so the elevation can come from other than the liver. Any disease or destruction of these can elevate this enzyme in the blood.

Here's a good link on ALP. If can also look up other lab test on this site. Look up Liver Enzyme tests and you see that one of the LFT's can be elevated as a result of Wilson's disease, which is a disease where there's an accumulation of copper in the body. But basically, there are other blood test needed to further evaluate the function of the liver.

http://www.drkaslow.com/html/alkaline_phosphatase.html

I also posted on another thread where the zinc to copper ratio is important. Iron, zinc and copper require a delicate balance. Your doc should check your zinc levels as well as the copper/zinc ratio.

But to directly answer your first question, John's liver enzymes were never elevated when his FE was high. His was high like yours.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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