Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > MDS
Register FAQ Search Today's Posts Mark Forums Read

MDS Myelodysplastic syndromes

Reply
 
Thread Tools Search this Thread
  #1  
Old Fri Nov 15, 2013, 01:13 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
The WT1 gene and Vidaza response

Hi All,
Several studies have showed that peripheral blood WT1 microRNA expression high patients will show inferior response rates when they are treated with Vidaza. Here is the latest one.
https://ash.confex.com/ash/2013/webp...aper57110.html
Kind regards
Birgitta-A
Reply With Quote
  #2  
Old Fri Nov 15, 2013, 11:46 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,556
They recommend "alternative treatments" for such patients, but of course MDS patients don't have very many treatment choices.

Still, it's important to know any predictors that correlate with success or failure of a given treatment, so doctors and patients can decide on the "order of preference" of whatever treatment choices there are.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Greg H - Vidaza as a Bridge to Transplant Greg H Transplants 54 Sun May 7, 2017 10:42 PM
Vidaza resistance Birgitta-A Drugs and Drug Treatments 3 Sun Jun 10, 2012 02:50 PM
DNA methylation of WT1 gene and Vidaza Birgitta-A Clinical Trials 4 Fri Nov 11, 2011 01:55 PM
Vidaza + valproic acid Birgitta-A Drugs and Drug Treatments 1 Thu Aug 4, 2011 03:49 PM
Correlation between gene expression and Vidaza responsiveness Birgitta-A Drugs and Drug Treatments 0 Wed Oct 7, 2009 02:03 PM


All times are GMT -4. The time now is 01:58 PM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org