huge lymph nodes for 4 weeks

[Ellen McDonough]

I have had severe aplastic anemia for a little longer than 2 years. I have been in partial remission with platelets and white cells not really ever back.Over the last 4 weeks I have developed growing numbers of lymph nodes all over my body.They are getting larger and larger.People say I "Look good" but I am more tired than the usual AA fatigue and have had paresthesias[numbness/burning] in my face ,hands feet for 3 months.My counts have been rising despite the same regimen of Gengraf .I was running for several months---- platelets 50-60, wbc-2.5-3.2 and hgb-10-11 and hct-32-33. All of a sudden I have jumped up to wbc-4.5 and platelets of 88.
Not bad but with weight loss for no reason , fatigue and these huge lymph nodes -under my arms, behind my knees, groins , elbows and neck I am wondering if this could be some sort of leukemia or cancer.Has anybody experienced this? I have not had fevers or night sweats. The node under my right armpit is HUGE-It sticks out through shirts!I have been to see my oncologist ,infectious disease doctor .Oncologist says it's"Viral" although no other viral symptoms and my labs don't show signs of infection.Infetious disease doc says not viral and we need to biopsy .So am scheduled for biopsy.I was wondering if anyone has had aplastic anemia and then gotten acute myelocytic leukemia -what are the symptoms?PET scan was negative but was taken 2 1/2 weeks ago-maybe too early to show anything ?Now I have WAY more nodes and they have grown HUGE!!!
Thanks-Ellen

[rschem]

I had saa aug/2008 was treated with ATG Sept/2008.
My palatletes have been as high as 150 Oct/2010 now are dropping to 109. I did not have any side efects from sandoz cyclosporne except tremors mouth sores and hair growth all are now less. I do have some pimple size bumps on my face .I don't know if they are a result of the cyclosporne .Does anyone elese have odd bumps since cyclosporne? I haven't asked My DR yet but will.

[kathrnclark]

I got a major lymph node infection after three weeks post-ATG. It turned out I was a carrier for Epstein Barr Virus. Have you ever been tested? We treated it with tylenol extra strengh and prednisone for a few weeks and it really helped.

[Ellen McDonough]

Still have big lymph nodes all over my body[6 weeks now].Had lymph node biopsy and thank God no lymphomas or Hodgkins or other cancers so far.It showed sinus histiocytosis with germinal centers. Also have had paresthesias on hands ,legs ,feet and around my mouth and chin[feels like I have been numbed up at the dentist} and swollen achy joints,very itchy skin for months now. Anyone ever had these symptoms or diagnosis? I was diagnosed with severe aplastic anemia in 4/2009 and received treatment with horse ATG,Gengraf and GCSF initially.Have been in partial remission since 9/2009.Still on Gengraf but everything else is finished long ago.
The node they removed was 2cm from right axiliae.The other lymph nodes are quite big as well.
My doctors seem to not know what is causing these symptoms so far.Still waiting for more path results and tests.