VIDAZA plus other

[slip up 2]

does anyone on Vidaza take other drugs for boosting red blood cells.....eprex?
thanks

[Birgitta-A]

Hi slip up 2,
Vidaza can be combined with EPO drugs. I have 5 abstracts about trials with Vidaza + EPO drugs. The results seem to be better for high risk patients. Do you want info about high or low risk patients?
Kind regards
Birgitta-A

[slip up 2]

Thanks Birgitta....we are at the stage we do not know high or low....spouse has 8 sets of Vidaza and for 5 months all has been well, counts started to fall last month, and again this month with 5 rbc x....2 BMB in the last month have shown nothing and less than 2 percent blasts and monosomy 7 not showing up at all anymore....he feels good and looks good....we are all perplexed....
Thanks

[slip up 2]

Brigitta...sorry high risk....I seem to be in a bit of a flap....
Thanks

[Birgitta-A]

Hi slip up 2,
The first study has very few patients - only ten - but a response rate of 60%.
http://ash.confex.com/ash/2010/webpr...aper28898.html

The second study is retrospective - they started to look at patients after treatment - and found that 44% of EPO and 29% of no-EPO patients reached hematologic improvement.
http://www.ncbi.nlm.nih.gov/pubmed/22177456

EPO drugs can be positive for high risk MDS patients.
Kind regards
Birgitta-A

[slip up 2]

Thank-you Birgitta, you are a gem and a fountain of information....

[Birgitta-A]

Hi slip up 2,
Thank you for the kind words ! Perhaps your spouse will be able to try an EPO drug and that the hgb will increase!
Kind regards
Birgitta-A