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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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  #1  
Old Wed Mar 7, 2012, 07:59 AM
cheri cheri is offline
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Location: Tuckahoe New Jersey
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Aranesp vs Procrit

Hi all~

After about a year on Aranesp, with no appreciable results, we have switched to Procrit...anyone have any idea how long these agents take to work? Anyone noticed a difference between the two, success rates, etc.

Thanks!
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Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
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Old Wed Mar 7, 2012, 08:54 AM
Birgitta-A Birgitta-A is offline
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Aranesp/Procrit

Hi Cheri,
The Nordic MDS group recommends
"Start with Aranesp or a similar drug alone for 8 weeks. In case of no response, addition of Neupogen for another 8 weeks. If no response after 16 weeks, treatment is terminated."

Hope you feel OK!
Kind regards
Birgitta-A
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Old Wed Mar 7, 2012, 09:37 AM
cheri cheri is offline
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Hi Birgitta--you are always "Johnny on the spot!"

Sheesh! What a racket! I have been on Aranesp and Neupogen for over a year! They said Aranesp took a long time to work, but after 16 weeks they should have terminated it?

Well, I'll give the Procrit a few months (getting it weekly now) and if there is not improvement, I'll discontinue it. Everything had side effects....Why take something that has no benefits? The only benefit seems to be to someones' bottom line! $$$
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Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
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Old Thu Mar 8, 2012, 03:40 PM
Birgitta-A Birgitta-A is offline
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Aranesp Procrit

Hi Cheri,
It is really very true that all drugs have side effects. FDA is warning against Aranesp and Procrit (they can cause cancer) but not in MDS patients. This can happen when the doctors try to increase HGB to normal values in for example patients with breast cancer.
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Birgitta-A
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