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#1
Tue Oct 8, 2013, 12:58 PM
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Vitamin K2 and blood transfusion
Hello, my mother has recently started taking Vitamin K2-MK4. Will this interfere with the blood transfusions that she receives, is there a risk of clotting?
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014 
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#2
Tue Oct 8, 2013, 03:20 PM
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From what I've read (and on the bottle of K2 I bought), it says do not take if you are on the blood thinner coumadin...
Based upon that, it appears to help with clotting and prevent thinning... Also when I met with my transplant pharmasist, I told him that I was taking K2 as a supplement (in addition to Folate, B-complex, D3 & Multivitamin), and he said that was fine up until the transplant, but definitely no K2 after or during TBI & chemo or post transplant...
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Married, father of three daughters; now 46; diagnosed w/ Major form MDS 6/18/2013; had low counts across the board; Multiple chromosome abnormalities; Finished 2nd round Dacogen 9/13; SCT - Oct. 31, 2013; Sibling match 10/10  ; 5.5% blasts down to 3%, now 1% (post BMT)
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#3
Tue Oct 8, 2013, 04:24 PM
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From what I understand, and what was stated on the recent webinar on alternative/complementary medicine, Vit K2 does not increase the risk of blood clotting. Vitamin K1 is needed for proper blood clotting. But even K1 will not increase the risk of blood clots.
The warning is really for those on blood thinners since taking K1 can counteract the action of the drug making it difficult for them to adjust the dosage to obtain the therapeutic blood thinning effect. If you take K1 while on blood thinners, you may have to increase the dosage of the drug.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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#4
Wed Oct 9, 2013, 04:36 AM
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Thanks whizbang, Marlene.
Just checked with the doctor as well, there is no problem for her to take the k2. Transfusion day today so just being a bit cautious.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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