Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > Bone Marrow Failure
Register FAQ Search Today's Posts Mark Forums Read

Bone Marrow Failure Causes, treatment approaches, terminology, related diseases

Reply
 
Thread Tools Search this Thread
  #1  
Old Wed Feb 12, 2014, 11:30 AM
Carlito Carlito is offline
Member
 
Join Date: Feb 2014
Posts: 3
Moms leukemia came back 5 months after transplant

Need some advice. My mother was diagnosed last February. She did the transplant in September and was fine till this last Monday when they found blasts in her blood (31%)

Her donor was unrelated but they said perfect match. My mom is 62. We are both devastated with this news. Does she have a chance to get through another round of induction chemo? Any chance if they do another procedure she will be ok? Just looking for some answers/help. She has fought so hard. Is their hope?
Reply With Quote
  #2  
Old Thu Feb 13, 2014, 06:58 PM
NLJabbari NLJabbari is offline
Member
 
Join Date: Aug 2006
Location: San Jose, California
Posts: 139
Carlito, sorry to hear about your mom's relapse. Have you tried posting this question on Facebook's
"Bone Marrow and Stem Cell Transplant Survivors Club"

https://www.facebook.com/pages/Bone-...33642656665802

Hope they'll be able to give you advice or answer your questions. Please come back and let us know what you learn and how your mom is doing.

Best of Luck!!!
__________________
06/2004 my son was dx with SAA at the age of 10. No sibling BM match. He underwent ATG (H)/CsA. Relapsed 05/12 & dx'ed w/PNH. Currently in wait/see mode for Solaris as he is asymptomatic...
Reply With Quote
  #3  
Old Fri Feb 14, 2014, 02:50 AM
DanL DanL is offline
Member
 
Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Carlito,

I am very sorry to hear about your mother's relapse. There are several different ways to treat a relapse, depending on your mother's overall health and the strategy that the doctors believe is in her best interest. Here are a few that I have read about and discussed with my team recently: 1) Donor Lymphocyte Infusion (DLI), which is where you are given a dose of your donor's lymphocytes to try and boost the transplant. 2) usually accompanied by a DLI, reduction of any anti-rejection drugs such as tacrolimus, sirolimus, MMF, cyclosporine, etc, to try and let the donor's marrow have a little more leeway and maybe knock out the blasts 3) vidaza or decitabine to try and bring the blasts back down and give the donor cells a chance to fight again, 4) second transplant - may or may not be accompanied by induction chemo, 5) experimental treatments for AML in relapse - there are many trials out there. This is obviously not an all inclusive list by any stretch, but may allow you to begin conversations with the doctors. If you are not comfortable with the responses (or maybe even if you are) second opinions may be helpful. There may be something that the doctors are missing and just need another set of eyes on her case.

Wishing you and your mother the best of luck!
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
Reply With Quote
  #4  
Old Fri Feb 14, 2014, 08:03 PM
Carlito Carlito is offline
Member
 
Join Date: Feb 2014
Posts: 3
Thank u guys for the responses. Her blasts are now up 71% and she was admitted tonight. However the plan is to use a pill called sorafenib. Problem is this drug takes time to order and they didn't want her to wait 5-7 days so they wanna start at hospital. She will be also taking hydroxyurea and allopurinol.

Anyone here familiar with that stuff? I'm hoping she can get into remission so she can try DLI.

As far as overall health she's in good shape otherwise. However they said the leukeimia is spreading fast so they wanna get moving and not wait for pills to come in. Once they do she can go home.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
16 months past SCT and doing fairly well. The sage of my transplant, start to now rar MDS 7 Wed Nov 18, 2015 11:26 PM
New to site, Transplant Disappointment & Worries sveness Transplants 2 Sun Mar 4, 2012 12:05 PM
NMDP Provides Transplant Information Marrowforums Transplants 1 Tue May 8, 2007 05:00 AM


All times are GMT -4. The time now is 11:32 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org