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MDS Myelodysplastic syndromes

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Old Sun Apr 6, 2014, 02:52 PM
ccnarayanan ccnarayanan is offline
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Location: Bangalore, India
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MDS treatment algorithm

Considering that MDS is a condition with so many inter-related parameters, it is difficult (even for highly qualified medical professionals) to prescribe a clear treatment path.

I came across a few links on this topic, particularly the following:

http://emedicine.medscape.com/article/2006494-overview - the best I have seen so far although it doesn't have a flowchart

http://www.meniscus.com/mei/ceofferi..._Algorithm.pdf.

http://www.usask.ca/cme/learning_res...Guidelines.pdf

I would appreciate the members' perspectives and inputs.
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Father, 83, dx MDS RCUD (RBC) monosomy 7+del7q+del20q Feb 2014, transitioned to RCMD (RBC+platelet) Apr 2014, started Decitabine on 21-Apr-2014 at 2/3rd the recommended dosage on Regimen 2 with no response, terminally ill and transitioned to hospice care on 30-Apr-2014, passed away on 18-May-2014.
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Old Mon Apr 7, 2014, 09:02 AM
Birgitta-A Birgitta-A is offline
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MDS

Hi ccnarayanan,
They all seem to be OK except that nr 2 "MDS Treatment Algorithm" recommends SCT for low and Interm-1 patients.

I don't think that is generally accepted. After 5 years more patients from this group have survived with the best possible care compared to the SCT patients.
Kind regards
Birgitta-A
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