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Old Sat Feb 17, 2018, 07:26 PM
lisa3112 lisa3112 is offline
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Cyclophosphamide for gvhd

Hi, reading the paper this morning in Melbourne and saw this article. Tried to upload picture of the article but didnt work. Its from the Alfred hospital in Melbourne. I am lucky enough not to have gvhd, but I know many of you do. They are doing a trial now.
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Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
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Old Sat Feb 17, 2018, 07:35 PM
lisa3112 lisa3112 is offline
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I had to crop the article to let it fit, so just a couple of paragraphs on the drug.
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File Type: jpg 20180218_111658-1.jpg (112.3 KB, 3 views)
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Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
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Old Sat Feb 17, 2018, 11:01 PM
rar rar is offline
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It appeases that it is used mostly for prevention rather than treatment of steroid refractory GVHD that I have had for nearly 3 years. I will show it to my doctor on Monday"s visit. Here are some articles on it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138214/

https://www.ncbi.nlm.nih.gov/pubmed/15696180

https://www.ncbi.nlm.nih.gov/pubmed/26764356
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