Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > AA
Register FAQ Search Today's Posts Mark Forums Read

AA Aplastic anemia

Reply
 
Thread Tools Search this Thread
  #1  
Old Mon Jun 9, 2014, 12:37 AM
Hopeful Hopeful is offline
Member
 
Join Date: Jan 2009
Location: California, USA
Posts: 769
Magnesium Tips?

Hi,

I am struggling with falling serum magnesium levels as a result of my long-term cyclosporine use. I currently supplement with 750 mg/day of Magnesium oxide, spread out in the morning and evening. Despite this level of supplementation and a current low dosage of cyclosporine, my magnesium is down to 1.3 mg/dl.

Does anyone have advice on foods that may increase (or decrease) magnesium absorption? Also, I would be interested in brands/types of magnesium that may have better absorption.

Thanks in advance for any tips!
__________________
58 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
Reply With Quote
  #2  
Old Mon Jun 9, 2014, 02:52 AM
DanL DanL is offline
Member
 
Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Hopeful,

I am on 4 grams per day to fight off the effects of Tacrolimus, and maintain a concentration of about 1.9. The items that were recommended to me were nuts and fish.

There are also a couple of decent articles here that covers magnesium absorption and diet:

http://www.ancient-minerals.com/magn...es/absorption/

http://www.ancient-minerals.com/magnesium-sources/

Vitamin D deficiency is mentioned as a possible cause of poor absorption, which is interesting as well.

Hope these help.
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
Reply With Quote
  #3  
Old Mon Jun 9, 2014, 07:58 AM
Bhutt Bhutt is offline
Member
 
Join Date: Apr 2013
Location: Canada
Posts: 44
I'm on 2520 Mg a day 840 morning noon & evening they recommend Swiss 420.
Don't know if this helps or not.

Blair
Reply With Quote
  #4  
Old Mon Jun 9, 2014, 09:37 AM
Marlene Marlene is offline
Member
 
Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,412
Look into more absorbable forms like magnesium glycinate, citrate, taurate or aspartate.

Kirkman labs has a good mag glycinate. There's a good product called Calm that is mag citrate.

Also consider epsom salt baths. Either whole body or just foot baths.

Like Dan stated, nuts are a good source too.

I've used the topical Ancient Minerals but found it irritating to my skin. Some have formulated a topical creams that feel better. I think Kirkman labs has one.
__________________
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
Reply With Quote
  #5  
Old Mon Jun 9, 2014, 07:07 PM
Rasmusbja Rasmusbja is offline
Member
 
Join Date: Aug 2013
Location: Copenhagen, Danmark
Posts: 4
Try magnesium citrate

Hi hopeful

I have had a huge struggle keeping my magnesium levels up due to my tacrolimus intake. I had to go to the hospital every week to get IV magnesium.

The hospital recomended some magnesiumtablets containing magnesium oxide, which I ate for a couple of months. However, they didn't help me at all, and I started a more scientific approach to my problems.

After searching pubmed.org for a couple of hours, I found out that magnesium oxide has a bioavailability of only 4%!!

A much better complex is magnesium citrate. I don't recall the bioavailability, but it was many times better than oxide.

So I found some magnesium citrate on the internet (couldn't find antydning in my country), and ordered it home for testing. And amazingly it works very well! I now have a magnesium level in my blood that is within normal range, even though i take the same amount of tacrolimus as usual.

So I would recomend to try and get some magnesium citrate. And if you do, please let us know if it works for you.

Best of luck
/Rasmus

(Sorry for spelling errors... Autocorrect is set to Danish )
__________________
33 y.o. male. Diagnosed with AA february 2013 - h-ATG + cyclosporin. Almost complete recovery but relapse after two months. Diagnosed with hypo-MDS monosomy 7 june 2013. MUD BMT september 2013. Another relapse to AML dec 2014 followed by flag-ida induction chemo and RIC BMT.
Reply With Quote
  #6  
Old Tue Jun 10, 2014, 12:18 PM
Hopeful Hopeful is offline
Member
 
Join Date: Jan 2009
Location: California, USA
Posts: 769
Thank you everyone for your suggestions!

I also have read about the low bioavailability of magnesium oxide, but that is the only form that my doctor recommends. I went to my local health food store and picked up some Mg oxide combined with Mg citrate. I am hoping that will help with the absorption. I also have cut out black tea and increased my water intake to combat the negative effects of cyclosporine on my kidneys. I already take Vitamin D supplements, but should probably recheck that level.

I will continue to eat a lot of nuts, greens, and chocolate and will give the epsom foot baths a try.

I don't think I am ready to cut out the coffee, but am questioning whether I should be washing down my medications with a latte!

I'll let you know how it goes!
__________________
58 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
Reply With Quote
  #7  
Old Wed Jun 11, 2014, 08:48 AM
tom30 tom30 is offline
Member
 
Join Date: Sep 2010
Location: Brooklyn, New York
Posts: 108
I noticed a while ago that the itchy foot problem I get from time to time was relieved almost magically by epsom salts foot soaks. I now take this product which comes with instructions on intake on the package. I've asked my doctor about it and he said as long as I did not exceed the RDA he had no issues with the supplementation, i had mag levels checked at my last visit but that was after I had been on supplementation for 6 months and I do not have the results nor a baseline to compare to. Here is the product I use. Natural Vitality Natural Magnesium Calm http://www.amazon.com/gp/product/B00...?ie=UTF8&psc=1
__________________
Tom- 62 yrs old, dx-eosinophilic fasciitis 2004, 1 yr prednisone resolves EF- now low counts, HGB has been ok... EF has been associated with MDS along with AA.
Reply With Quote
  #8  
Old Tue Jun 17, 2014, 12:33 PM
Hopeful Hopeful is offline
Member
 
Join Date: Jan 2009
Location: California, USA
Posts: 769
Update :)

Less than 2 weeks ago, my Mg was down to 1.3 mg/dl.
I just had it retested and am up to 1.9 mg/dl!

I only increased my supplementation from 750 mg to 900 mg. So, I don't think this was the reason. I am now using different brands of magnesium, one which includes magnesium citrate and oxide. I think the biggest effect may be from cutting out black tea and drinking LOTs of water. Previoiusly, I was drinking water like-a-normal-person because my dosage of cyclosporine is so low. However, I have read (and now seen) that the *duration* of cyclosporine use at any dosage also plays a part in impared Mg reabsorption in the kidney.

The moral of the story: Drink lots of water!
__________________
58 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Magnesium tom30 Alternative Treatments 7 Sat Jan 14, 2017 09:18 PM
Tips to manage decitabine / Dacogen side effects / enlarged spleen issues? Strength14 Drugs and Drug Treatments 1 Sun Jul 6, 2014 10:15 PM
Magnesium Marc R AA 7 Sat May 3, 2014 02:45 AM
SCT hospital survival tips bettyliz Transplants 5 Thu May 17, 2012 10:35 AM
Survival tips for your hospital stay bettyliz Spouses and Caregivers 0 Thu May 10, 2012 10:59 PM


All times are GMT -4. The time now is 01:29 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org