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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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Old Sun Mar 17, 2013, 08:33 PM
kgtuck kgtuck is offline
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Location: Sylva & recently Waynesville, North Carolina USA
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Oral form of Dacogen/Vidaza??

Last week my husband tuned in to a webinar presented by the Leukemia-Lymphona Society and they reported that there is currently a "clinical trial for an oral solution of a methyltransferase inhibitor." We assume that would mean dacogen/vidaza??? But they really didn't say what drug it was. Has anyone out there heard or read of such a trial ? Not complaining, tho, I am thankful for this drug keeping me healthy, but pill form would be nice!
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66 yr female;diag 6/09; MDS, unspecified, normal cytogenetics: blasts 10%; successful Dacogen;every 4th wk.; as of Aug.'12 changing to every 5th wk., stable at Hgb 12-14/platelets 200-300/wbc 2.-3.
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Old Mon Mar 18, 2013, 10:14 AM
Birgitta-A Birgitta-A is offline
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Oral Vidaza (azacitidine)

Hi kgtuck,
As far as I understand they only take "new patients" into studies to be able to examine the effects of the drug.
http://www.clinicaltrials.gov/ct2/sh...cr=Open&rank=1

Here are results from a study:
https://ash.confex.com/ash/2012/webp...aper51734.html

Kind regards
Birgitta-A
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Old Mon Mar 18, 2013, 11:02 AM
kgtuck kgtuck is offline
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Thanx, Birgitta

Thanx so much for the information. I thought that the drug was probably Vidaza since it has been "out there" longer. It's just nice to know that more and more research is being done. Take care!
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66 yr female;diag 6/09; MDS, unspecified, normal cytogenetics: blasts 10%; successful Dacogen;every 4th wk.; as of Aug.'12 changing to every 5th wk., stable at Hgb 12-14/platelets 200-300/wbc 2.-3.
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