Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > MDS
Register FAQ Search Today's Posts Mark Forums Read

MDS Myelodysplastic syndromes

Thread Tools Search this Thread
Old Fri Jan 18, 2008, 03:43 PM
Joan Joan is offline
Join Date: Jan 2008
Location: Ames, Iowa
Posts: 35
Husband's MDS

Hi, I posted my husband's story under "My Story". Now I have a question about MDS. Don sometimes runs a fever in the evening with his MDS. Dr. isn't concerned. In fact, has said on a couple of occasions we don't need to seek medical advice unless he is delirious or fever is up to 105. Any of you have similar experiences?
Reply With Quote
Old Fri Jan 18, 2008, 08:54 PM
kertkkey2007 kertkkey2007 is offline
Join Date: Jul 2007
Location: Rome, Ga
Posts: 28
Hi Joan

My husband Kert has had MDS going on 4 yr's. now and the Dr. has always told us to go to the hospital if his fever goes up to 100.5> I've took him once or twice and they admitted him and started an IV to fight infections. It is because his White Blood counts get's down to 1. and one time .8 He has the most trouble with the White and platelets. Good luck and God Bless
Reply With Quote
Old Sat Jan 19, 2008, 11:29 AM
Joan Joan is offline
Join Date: Jan 2008
Location: Ames, Iowa
Posts: 35
Hi Kertky 2007

thanks for reply. Don's white blood count is usually in the 3's and 4's. Dr. has never been too concerned about them.

Reply With Quote
Old Sat Jan 19, 2008, 12:56 PM
Birgitta-A Birgitta-A is offline
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918

Hi Joan,
Fever during the night can depend on that the so called cytokines are more active when we sleep. Cancer cells can spontaneously produce cytokines, small proteins with multiple biological properties. Some cytokines released by cancer cells are "pyrogenic", they produce fever directly by their action on the hypothalamus, which is involved in regulating body temperature. Then the fever isnīt a reason to worry.

If your husband has an infection you should worry. I understand that his WBC:s including the neutrophils are OK and then this info from a MDS-site perhaps isnīt relevant.

“For aplastic anemia, myelodysplastic syndromes and PNH patients, there is no absolute number at which an elevated temperature becomes critical. The most important issues are:
what is your absolute neutrophil count?
what is your absolute lymphocyte count?
do you have a central line or some other "foreign body" in you?
are you having symptoms (chills, low blood pressure, sweating, rapid breathing)?
do you have a source for infection on your physical examination?

Persistent fever should be considered to be an indication of infection until proven otherwise. Indwelling cathers can often be a source of asymptomatic infection. A diligent search for infection should be undertaken. Occasionally fevers can be associated with disease progression to acute leukemia. Fever can also follow transfusions.”

Kind regards
68 yo, MDS Interm-1 dx May 2006, transfusion dependent, Desferal 4 days after transfusion every 6th week, Neupogen 2 injections/week, asymptomatic
Reply With Quote

Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
MDS - VA assigns diagnostic code 7725 Tommy Daniels MDS 4 Sun Jan 22, 2017 03:51 PM
New Tool: MDS Classification Marrowforums Site Announcements 7 Tue Jan 4, 2011 05:12 AM
Husband's MDS Joan Tell Your Story 6 Mon Feb 11, 2008 02:05 PM

All times are GMT -4. The time now is 02:34 AM.

Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2021, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright Đ 2006-2020 Marrowforums.org