Home         Forums  

Go Back   Marrowforums > Treatments > Drugs and Drug Treatments
Register FAQ Search Today's Posts Mark Forums Read

Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

Reply
 
Thread Tools Search this Thread
  #1  
Old Fri Jul 2, 2010, 12:40 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Orphan drug designation for Sapacitabine

Hi all,
Now the new drug Sapacitabine has been granted orphan drug designation for the treatment of both AML and MDS.
http://production.investis.com/cyc/i...10/2010-07-01/
Kind regards
Birgitta-A
Reply With Quote
  #2  
Old Fri Jul 2, 2010, 01:21 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Just last month Cyclacel Pharmaceuticals, the manufacturer of Sapacitabine, announced the results from a Phase II study. Sapacitabine was found to help MDS patients who failed to improve with hypomethylating agents: azacitidine, trade name Vidaza, and decitabine, trade name Dacogen.

Sapacitabine works by damaging the DNA of cancer cells, preventing the cells from multiplying. For the technical minded, it's a nucleoside analogue that interferes with the DNA polymerase enzyme.

Phase II studies assess how well a drug works with different does. For Sapacitabine, a Phase III study in a larger patient population comes next. Phase III studies measure how effective a drug is compared with the treatment patients would otherwise get. MDS patients who have failed Vidaza and Dacogen currently have no good options, so this brings new hope for further effective treatment.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
AMY-101 for PNH Gains Orphan Drug Status Marrowforums PNH 0 Wed Nov 26, 2014 01:01 AM
T-cell therapy for leukemia gets orphan drug designation Birgitta-A Drugs and Drug Treatments 0 Thu Nov 20, 2014 11:51 AM
What is the case FOR drug therapy?? GaryV Drugs and Drug Treatments 11 Thu Nov 4, 2010 08:37 PM
Anti-fungal Inhalation Powder Granted Orphan Drug Status Marrowforums News and Events 0 Sun Oct 1, 2006 02:18 AM


All times are GMT -4. The time now is 05:47 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org