Best treatment options for conversion to AML

[Pam Wishart]

Hi,
A friend has recently converted to AML and we're getting together all the possibilities/options he should be discussing with his haematologist on the 11th. Any suggestions in addition to Vidaza and a PBSCT?
Thanks, Pam W. (MDS, dx February 2000)

[Neil Cuadra]

Hi Pam. Good to see you around here.

About your friend, what's his age? What were his previous diagnosis and treatments?

[Pam Wishart]

Hi Neil,

Probably in his early 60s and was on Thalidomide for years, then switched to Revlimid despite no abnormal chromosomes. We're meeting tomorrow to go over his list.

I need to participate more in Marrowforums - I'm just lazy and found the list easier!

All the best to you and Ruth.

Pam

[Neil Cuadra]

User Harold P (a couple named Sandy & Pete) had a similar situation after he was diagnosed with secondary MDS. They considered a mini-tranplant (ruled out due to other health problems), watch-and-wait, Vidaza (azacitidine), and Dacogen (decitabine). Unfortunately, they haven't posted recently so we don't know how things turned out. You'll find a few forum threads discussing the choice between Vidaza and Dacogen.

After "what treatment do you recommend and not recommend?" the most important question to ask is "Why?"

[Steve Kessler]

There is a study currently recruiting combining azacytadine, romiplastim and mylotarg at the Fred Hutchinson Cancer Research Institute here in Seattle and also elsewhere. Check it out at nih.gov.