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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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  #1  
Old Fri Jun 27, 2008, 01:44 PM
Birgitta-A Birgitta-A is offline
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Exclamation Updated warning for Aranesp and similar drugs

Hi all,
Unfortunately Aranesp and similar drugs seem to give more complications and EMEA (corresponding to FDA in Europe) is updating the warning:

http://www.emea.europa.eu/pdfs/human...33396308en.pdf
Kind regards
Birgitta-A
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  #2  
Old Fri Jun 27, 2008, 03:54 PM
Marlene Marlene is offline
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Thanks for posting this.

Marlene
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of January 2017, FE is 233, HGB 11.7, WBC 5.1/ANC 4.0, Plts 90K.
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  #3  
Old Sat Jun 28, 2008, 05:25 AM
Birgitta-A Birgitta-A is offline
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Warning for Aranesp

Hi Marlene,
The question of giving erythropoiesis-stimulating agents like Aranesp is very complicated . From one of the other four support groups I belong to we got this abstract today:
http://theoncologist.alphamedpress.o.../13/6/715?etoc

The insurance companies will probably be still more restrictive with permission to give Aranesp in the future.
Kind regards
Birgitta-A
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Old Sat Jun 28, 2008, 09:29 PM
Zoe's Life Zoe's Life is offline
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I think this is the same info the US looked at several months ago. There was debate about whether or not it affected MDS patients. It was decided it did not present a problem for MDS (and I think other non-tumor cancers).

Zoe
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Old Sun Jun 29, 2008, 05:19 AM
Birgitta-A Birgitta-A is offline
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Aranesp

Hi Zoe,
I hope you are right but this sentense makes me wonder: "Epoetin-containing medicines are indicated in patients with chronic renal failure and for the treatment of anaemia in symptomatic patients with non-myeloid tumours receiving chemotherapy."
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Birgitta-A
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  #6  
Old Sun Jun 29, 2008, 09:20 PM
Zoe's Life Zoe's Life is offline
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Birgitta,

The US warnings said the same thing. Using it for MDS is an off-lable use, although after all this time I don't know why it still is.

Zoe
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