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MDS Myelodysplastic syndromes

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  #1  
Old Wed Jul 17, 2013, 05:37 PM
CarolineO CarolineO is offline
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Use of Steroids

Hello

As I mentioned in a previous post, after my dad's first chemo back in April he had a horrendous infection and has got weaker and weaker since, losing a lot of weight and interest in food and most activities with low counts of all cells.

His consultant took another bone marrow biopsy two weeks ago, expecting to see his blasts had increased and he had progressed to AML. However his blasts had dropped from 11 to 5%. He was then prescribed a steroid, Prednisolone, at 10mg for the first week then 5mg the second.

The change in my dad has been dramatic - he seems to have got rid of the catarrh and sickness that was making his eating so hard and is putting on weight. He is almost back to his 'normal' self in terms of being interested in life and activities. Although he was in a wheelchair two weeks ago he is now able to walk down the garden etc.

It is so wonderful to see him so much improved and I am wondering if it is just the steroids that have had this effect - has anyone else had similar experiences with steroids?
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Old Tue Jul 23, 2013, 01:36 AM
Cheryl C Cheryl C is offline
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I was on prednisolone for bacterial bronchitis for a couple of weeks back in 2011 and I certainly felt more energetic than usual.
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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Old Tue Jul 23, 2013, 02:12 PM
ssdavi71416 ssdavi71416 is offline
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Prednisone is amazing if you body is stiff it will make you feel like a new person. I think at a dose of 5 mg your father could be on it indefinitely, but there are side effects.
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Scott 51 yr SAA 3/2012. PTL 7, ANC 200. ATG finished 4/9/2012. 2/4/2013. TX independent:; PTL 133, ANC 3300, Hgb 13.4.
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