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Bone Marrow Failure Causes, treatment approaches, terminology, related diseases

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Old Fri May 29, 2015, 12:01 PM
gina66 gina66 is offline
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Join Date: Oct 2012
Location: Roland, OK
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Retic counts normalized after ATG and Cyclosporint

Hi everyone,

I would like to get some feedback regarding Retic count changed. I had ATG last January 2015 and started Cyclosporine at the same time. Since March 2015 my Retic count normalized. It changes between low normal to 1.6 consistently. Even when my cyclosporine level is low, my retic was even higher. I contacted my UCLA doctor about this and I am hoping to get some feedback too. I know some of you have successes with treatments. My question is how long does it take to normalize the Hemoglobin counts after seeing normalization of Retic counts? It has been 3 months since my retic counts improved but my hemoglobin counts is basically the same. I still needed blood transfusion until now. Thanks.
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PRCA, infected by Parvovirus. Took Prednisone 20-60 mg/day for 6 mos., Cyclosporine 100- 200mg/day for 6 mos., Exjade 1000-2500 mg/day current, Warfarin 3-4mg/day, Cyclophosfomide 50 mg/day for 4.5mos., Campath for 2.5 mos, Danazol 200-400 mg/day for 6 mos. Currently- Rituximab for 4 wks.
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Old Fri May 29, 2015, 07:52 PM
triumphe64 triumphe64 is offline
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Join Date: Feb 2008
Location: Dallas, Texas
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Gina,
I can't answer specifically, but I think ATG can take several months to really kick in. I'm basing this on what I have read over the years. I hope Dr. Paquette will be able to clarify this.
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Dallas, Texas - Age 75 - Pure Red Cell Aplasia since March 2005 - Tried IVIG - Then cyclosporine and prednisone. Then Danazol, was added. Then only Danazol . HG reached 16.3 March 2015. Taken off all meds. Facebook PRCA group https://www.facebook.com/groups/PureRedCellAplasia/
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