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#1
Fri Apr 25, 2008, 04:16 PM
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I need input re: HLA-C mismatch in donor
Hi everyone,
My son Evan is headed for transplant as ATG/Cyclosporin treatment has not worked for his sAA. Our donor is a 9/10 match with a mismatch at antigen C. Our transplant doctor is not overly concerned about this, as A, B and DRB1 all match. We are very concerned and worried to say the least and would appreciate any insight any one might be able to share. Thanks,
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Nicole, mom to Evan (20); diagnosed SAA November 2007, hATG mid-November 2007, no response after 6 months, unrelated 9/10 BMT June 2008, no GVH, health completely restored thanks to our beloved donor Bryan from Tennessee. www.caringbridge.org/visit/evanmacneil 
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#2
Fri Apr 25, 2008, 05:20 PM
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Oops, nevermind.
I just exchanged emails with the transplant doctor and I was wrong. The mismatch is at a much less important allele-DQB1. Still, any input is always appreciated. Thanks,
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Nicole, mom to Evan (20); diagnosed SAA November 2007, hATG mid-November 2007, no response after 6 months, unrelated 9/10 BMT June 2008, no GVH, health completely restored thanks to our beloved donor Bryan from Tennessee. www.caringbridge.org/visit/evanmacneil
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#3
Wed May 14, 2008, 03:00 PM
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Does he have a donor yet? We are about to face a transplant and was wondering if we will be going through it at the same time.
How is he doing?
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Guardian and Caretaker of my 14 year old sister with SAA;Diagnosed Oct. 2007-1 ATG/Cyclosporine treatment-10-07:Waiting on Bone Marrow Transplant-it's down to 2 potential donors;Now it's changing to early MDS-pre Leukemia.; She has now moved with our other sister to see a new dr in Nashville.
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