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#1
Sun Sep 8, 2013, 02:37 AM
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Pathology test result spikes
I did ask this question within another discussion but can't remember which one so I can check if there was any response!
Does anyone else with MDS experience sudden spikes in their pathology results? For example, usually my WCC is around 1.2-1.6 maximum. Twice this year I've had a spike up to 2.3 and 2.7 respectively. Other results remained fairly similar to usual. The following month the WCC was back down again. I wasn't doing anything different either time and didn't have an infection to my knowledge. Is this normal with MDS? and if so what causes it? Is it possible to have an infection and not know? Thanks.
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood. 
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#2
Sun Sep 8, 2013, 05:07 AM
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Cheryl,
You previously asked about it in the New Discovery on Increasing Platelets - Papaya Leaves thread. This is a better place to ask.
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#3
Sun Sep 8, 2013, 10:50 AM
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Cheryl
Hi - My WBC goes up and down like a yoyo - recently from 1.8 to 2.4 and my ANC has been below 1.0 and pretty consistanly .5 for over a year and recently its 1.2 - not sure how this really happens but it has for me too. Hope you are doing well - Susan
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Susan Patient, 58, MDS, UPDATED 9/13 Now have RAEB-2, Firbrosis 3+, blasts 18% peripheral, 10 - 14% blasts marrow, chromosomes now T 1:21, trisonomy 16 and 1.- Match found ---10/10 -couldn't believe when I heard - Tentative day is 1/09th!!!! Admit date changed to 11/12. WOW -
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#4
Sun Sep 8, 2013, 01:36 PM
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hello,
I think that is normal... Wcc range live are 1-2 days, platelets 10 days and rbc 120 days...so wcc counts can change rapidly in a day in function in your environnement for exemple (tabacco, alcohol,...) of your health that day.... In fact wcc are the health guards so they don't wait a big infection to work :-)... friendly, béné
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boyfriend with RARS-T dx 11/02//dx : hb 11,5; plt 870000, wh : 6500//Before fasting cure (13/04): hb: 8,9; plt 2200000; white:6000//After fasting cure (14/09): hb 12,5; platelets 400000, wh 3000.//Now (15/08) : hb : 11,plt : 650000, wh 3000// hydrea 1c/day and cardioaspirin, 1c/day,age: 56 y.
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#5
Sun Sep 8, 2013, 05:27 PM
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Tina wbc usually stays around 0.08 to 1.5 ( which is our new normal ) , every once and a while it will jump a point or so, then go back down, the doctors are looking more at the neutrophil, eosinophil, basophil, monocyte and lymphocyte numbers when determining whats going on with the wbc, doctors like to look for trends... not what happens on a week to week basis, still if your wbc come back 2.5 take the same precautions as you do at 1.2
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Billy - Husband of Tina: 31 years old at dx - June 2007 - Stage 3 Breast Cancer - Dec 2008 Stage 4 - Brain and Bone - Nov 2012 - Therapy Related AML. Curently on Decitabine for Therapy Related AML and Herceptain for ongoing Breast Cancer. Weekly transfussions of blood and platelets
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#6
Sun Sep 8, 2013, 10:35 PM
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Thanks for the speedy replies Marrowforums friends. It's always good to know that others are experiencing similar occurrences and that there's nothing to be concerned about. My ANC ranges between 400-700 so when it suddenly jumps to 1700 it's mind-boggling.
This forum is a fantastic blessing isn't it!
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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#7
Wed Sep 11, 2013, 01:12 AM
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I have also found inconsistencies in lab results. This week was a prime example. Lab results suggested that I needed a transfusion NOW. Doctor ordered CBC to be run again and the results were more in the range from prior weeks. So we don't know if it was a lab error or if perhaps the original sample was diluted from the port flush.
Sue
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Sue, age 72; Dx 6/2010 MDS Int-2. Revlimid unsuccessful, began Aranesp 10/2010; additionally Dx PNH 2/2011, Soliris added 3/2011. ATG 5/2011, Cyclosporine 5/2011. Nplate 10/2011 to 10/2012 . Exjade began 12/2013 due to high ferritin level, discontinued 3/2014 because of increase in creatinine.
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