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Old Thu Feb 5, 2015, 12:06 PM
Birgitta-A Birgitta-A is offline
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
CMV infection after SCT

Hi All!
Now they try to prevent CMV infection after SCT in mice in a new way: http://www.checkorphan.org/news/a-fe...ant-infections
Kind regards
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Old Thu Feb 5, 2015, 02:11 PM
Neil Cuadra Neil Cuadra is offline
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,492
What's impressive about their research is that they realized that it would be worth using less aggressive and less-differentiated memory T cells rather than using the tougher, mature, and more-specialized CMV-programmed T cells. They can apparently isolate the memory T cells that "know" about CMV.

Their theory is that the process they successfully used to provide CMV immunity in mice will be applicable to humans because CMV-specific memory T cells in mice and humans are genetically similar. Let's hope so!
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