Home         Forums  

Go Back   Marrowforums > Treatments > Drugs and Drug Treatments
Register FAQ Search Today's Posts Mark Forums Read

Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

Reply
 
Thread Tools Search this Thread
  #1  
Old Tue Nov 30, 2010, 05:43 PM
cheri cheri is offline
Member
 
Join Date: Nov 2010
Location: Tuckahoe New Jersey
Posts: 243
Vidaza--7 days reduced to 5?

Hello all
I have been informed, after my 4th month in treatment, that my Vidaza dosage schedule may be reduced from 7 days to 5 days, because my local hospital will be closing their infusion rooms on weekends. Clearly, I am upset that the treatment to save my LIFE is influenced over their budget issues....my Dr's office is also closed, as are other area hospitals....

Does anyone have an facts to substantiate that this reduced dosage will reduce my prospects for positive results? Or any other suggestions, such as a letter writing campaign to the hospital itself?

The widespread issue of limited staff/care at hospitals on the weekends is such a conflict of interests in helping people get well!
__________________
Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
Reply With Quote
  #2  
Old Tue Nov 30, 2010, 06:36 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Cheri,

Here is another forum thread discussing 5-day treatment because of the weekend.

It's awful that a change in treatment would result from budget issues like this, but the medical question (the ideal number of days) has not been settled. See the Vidaza 5 days vs 7 days forum thread.

Many patients get a 5-day treatment schedule, as mentioned in these forum threads:
Temodar and MDS and Vidaza (2007)

Vidaza for my 85 yr old mother with MDS? (2008)

Vidaza working great so far (2010)

Vidaza and my MDS/AML Treatment Mystry (2010)
Reply With Quote
  #3  
Old Tue Nov 30, 2010, 08:49 PM
cheri cheri is offline
Member
 
Join Date: Nov 2010
Location: Tuckahoe New Jersey
Posts: 243
Vidaza 7 vs 5 days...

Thanks Neil!
Like everything else that seems to be out of my control, I'll just roll with it and see how it all plays out... It may turn out to be more effective and less traumatic for my blood counts in the long run!
Everything happens for a reason...
__________________
Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
Reply With Quote
  #4  
Old Tue Nov 30, 2010, 11:55 PM
Chirley Chirley is offline
Member
 
Join Date: Oct 2007
Location: Logan City Australia
Posts: 1,100
Hi Cheri,

My treatment centre doesn't do any drug treatments on weekends, only blood products. So my doctor ordered 5 days on week 1 and then Monday and Tuesday on week 2.

I can't say if it effected my outcome or not but I'm no longer on Vidaza due to lack of response and increasing blasts.

Good luck.

Chirley
__________________
Copper deficiency bone marrow failure (MDS RAEB 1), neuromyelopathy.
FISH reported normal cytogenetics but gene testing showed
Xq 8.21 mutation
Xq19.36 mutation
Xq21.40. mutation
1p36. Mutation
15q11.2 deletion
Reply With Quote
  #5  
Old Wed Dec 1, 2010, 06:34 AM
Susan L Susan L is offline
Member
 
Join Date: Jun 2010
Location: Ga
Posts: 245
Cheri

Hi again - I am on the five day cycle of Vidaza. Not sure what difference it makes - maybe it will be less traumatic to the blood lines for ya. Talk to ya later.
__________________
Susan Patient, 58, MDS, UPDATED 9/13
Now have RAEB-2, Firbrosis 3+, blasts 18% peripheral, 10 - 14% blasts marrow, chromosomes now T 1:21, trisonomy 16 and 1.- Match found ---10/10 -couldn't believe when I heard - Tentative day is 1/09th!!!! Admit date changed to 11/12. WOW -
Reply With Quote
  #6  
Old Wed Dec 1, 2010, 07:54 AM
Greg H Greg H is offline
Member
 
Join Date: Sep 2010
Location: North Carolina
Posts: 660
Five plus 2

Hey Cheri,

I'm not doing Vidaza at this point, but I can report that the non-metro clinic I rely on is also closed on weekends. Their standard approach to Vidaza is five days, take the weekend off, and complete the set of seven on Monday and Tuesday.

Take Care!

Greg
__________________
Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
Reply With Quote
  #7  
Old Thu Dec 2, 2010, 12:49 AM
mausmish mausmish is offline
Member
 
Join Date: Mar 2010
Location: Maryland
Posts: 453
Hi Cheri, I did 11 5-day cycles of Vidaza prior to my bmt with great success. I could have gone to a different facility for 7 but felt the 5-day was working well and causing no probes with side effects or counts so why change what works.
__________________
Karen, age 62, dx MDS RAEB-2 1/8/10: pancytopenia WBC 2.7k/Hgb 7.4/Hct 22.1/Plt 19k; complex cytogenetics -3,del(5)(q14q33),-6,+8,+mar,17% blasts. MUD BMT Johns Hopkins 11/30/10. Dx tongue cancer 8/31/12. ok now. blog mausmarrow.com
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Greg H - Vidaza as a Bridge to Transplant Greg H Transplants 54 Sun May 7, 2017 09:42 PM
Vidaza during 5 days every 14 days Birgitta-A MDS 0 Mon Nov 18, 2013 05:33 AM
When to stop Vidaza? Paolo D. Drugs and Drug Treatments 5 Sun Jun 26, 2011 02:15 AM
Vidaza 5 days vs 7 days Birgitta-A Drugs and Drug Treatments 11 Sat Feb 19, 2011 10:44 AM


All times are GMT -4. The time now is 07:07 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org