Home         Forums  

Go Back   Marrowforums > Treatments > Transplants
Register FAQ Search Today's Posts Mark Forums Read

Transplants Bone marrow and stem cell transplantation

Thread Tools Search this Thread
Old Sat Jun 30, 2018, 12:33 AM
JoMac53 JoMac53 is offline
Join Date: Sep 2017
Posts: 75
Genealogy DNA testing and stem cell transplants

I've just leaned about recipients' dna changing to donor's dna after stem cell transplants. So, if you're interested in dna testing for genealogical reasons, get tested before you have a transplant.


But this also brings up a questions and ideas. I've read about mutations showing up, or disappearing, after transplant. This could be the reason, of course. And also, in genealogy, they get matches by comparing your dna results to someone else's, including mutations. I wonder if this has anything to do with finding 'matches' for transplants.

It's late and this is too complicated of a topic for me right now, but just wanted to throw this out there to see if anyone else is interested.

My own journey to transplant is on hold while time tics by waiting for medicare coverage. Does make me rethink my non-belief in socialized medicine a bit.
Joanne, 65F, 8/17 dx Primary MDS-EB1, Pancytopenia; 6/19 MPN w/CMML characteristics, dr calling it AML even w/blasts <20%; 7/19 Induction w/Vyxeos resulting in complete remission with incomplete blood count recovery.
Reply With Quote
Old Mon Jul 2, 2018, 01:09 AM
lisa3112 lisa3112 is offline
Join Date: Jun 2016
Location: Melbourne
Posts: 105
Interesting! Didnt even think about genealogy testing after a stem cell transplant. As for mutations disappearing.. I had runx1 mutation prior to transplant, and I dont have it now.
Really sucks that you have to wait for Medicare coverage. Good luck and thanks for sharing. Lisa
Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
Reply With Quote
Old Fri Jul 6, 2018, 06:51 PM
GoodDay5150 GoodDay5150 is offline
Join Date: Sep 2014
Location: Centennial, CO
Posts: 131
I know that the tests that use saliva will not show accurate results bcse of the white blood cells in your saliva. I never did a genealogy test b4 my transplant, but my brother may do one sometime. I would be more curious abt that of my donor, who I have never communicated with. I am not trained in medicine but it would make sense that mutations would go away after a transplant. I do not envy those w/ medicare issues who need treatment. My current insurance carrier as well as the HMO I had when I had my transplant are pretty easy to work with.

Reply With Quote

Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

All times are GMT -4. The time now is 02:44 PM.

Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright 2006-2020 Marrowforums.org