Revlimid with Exjade

[CinJo]

My question: Is anyone using both of these meds at the same time and have they had any reactions to them.

I started Exjade in March of this year and added Revlimid in May of 2005. My platelets were normal before Exjade was added, now I have severe thrombocytopenia.

Thank you.
CinJo

[Covergirl]

Hi CinJo

I started Exjade in February. The only med I was taking for my RARS-MDS. In June, my ONC noted my WBCs decreasing. She took me off to the Exjade and my WBCs returned to what is normal for me. Lowering WBCs is not listed as a side effect for Exjade, but have heard at least one other MDS patient on another forum had the same problem.

Just an FYI,
--cheryl

[pjbutler]

You might try contacting the companies that manufacture the drugs. They are required to maintain databases of these reports and may have some information for you.

[Mike Lawler]

My wife has been taking EXJADE for 3 weeks and has just had a reaction. She has a rash over most of her body, a severe rash. She stopped taking the EXJADE and has been treated for the rash using Benadryl, EPI, steroids and Pepcid. I would like to ask if anyone knows how long we can expect the rash to remain.

[CinJo]

I started with Exjade in March and Revlimid in May. I was only able to take Revlimid (Revl) at 10mg for 10 days when platelets and WBC's lowered to the point where I needed Neupogen and Platelet transfusion. I was off Revl until my counts became acceptable in July and used Revl at 5 Mg for 20 days when the counts were again too low. At that point my hemo and I stopped Revl and Exjade. I was able to start Revl 7 days later (5 mg every other day in early August) as the counts became acceptable again and I stayed on it this time. My Hgb is 11.7; whites at 3.6 and the platelets are holding at 59. I haven't had a tx since early August. Before I started Exjade my platelets were normal and my whites were 3. I noticed that those two counts were slowly decreasing and not recouping when I had transfusions as they did previously prior to starting Exjade. Revlimid without Exjade has been successful for me.