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Transfusions and Iron Overload Blood and platelet transfusions, iron testing and treatments

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  #1  
Old Sun Apr 21, 2013, 11:49 PM
Calimom Calimom is offline
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Location: Los Angeles, California
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Transfusion Frequency...

My mom's had MDS and is has been requiring blood transfusions. While at my house the doctor would give her 1 unit of blood when she was in the 8s and that would last about 3 weeks. When she's with my sister they gave her 2 units and it lasted 6 weeks. Is it better to get 1 unit every 3 weeks or 2 every 6? I guess i'm wondering which scenario would your body process the excess iron better.

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Old Mon Apr 22, 2013, 11:18 AM
riccd2001 riccd2001 is offline
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Keep a detailed record...

All units of PRBCs are not equal. The volumes are different. The expiry dates are different.

It's important to keep a record of the dates of infusion, the volumes infused and the dates of PRBC donation and expiration. Keep a precise record; you may be quite surprised at the volume variations and just how long the transfusions "work" for your mom, just sayin'.

Your mom's doc should have standing orders for the number of PRBC units to infuse depending on her Hgb level. For example, two units when Hgb is under 80g/L.

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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
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Old Wed Oct 9, 2013, 08:36 AM
Mseth Mseth is offline
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Quote:
Originally Posted by riccd2001 View Post
All units of PRBCs are not equal. The volumes are different. The expiry dates are different.

It's important to keep a record of the dates of infusion, the volumes infused and the dates of PRBC donation and expiration. Keep a precise record; you may be quite surprised at the volume variations and just how long the transfusions "work" for your mom, just sayin'.

Your mom's doc should have standing orders for the number of PRBC units to infuse depending on her Hgb level. For example, two units when Hgb is under 80g/L.

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Thanks for educating us on this aspect.

I have now started looking at the volume on the pRBC pack. On the pack it has printed volume as 250-300 ml, some packs have an actual exact volume written, sometimes not written. When it's written it's around 270 ml or so. Is this the standard volume given?
Date of collection are within a couple of days prior to transfusion so I guess that is fine.
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Mother age 79, dx MDS RCMD low risk del 20q April 2013, no response to EPO, Danazol. pRBC tx dependent - 2 units every 3-4 weeks, exjade Dec 2013 - Mar2014, restarted Dec 2014
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  #4  
Old Wed Oct 9, 2013, 06:10 PM
riccd2001 riccd2001 is offline
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I can't answer for your location. I have my PRBC transfusions in Oakville Ontario Canada. Each bag is marked with the donation date, expiration date and volume.

I've had a bag with volume slightly below 250ml (248ml) and well over 300ml (361ml). In general the majority of bags I have received falls between 250ml and 300ml.
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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
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