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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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  #51  
Old Tue May 31, 2011, 12:14 PM
Lbrown Lbrown is offline
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Good luck Gustav!

Deb
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  #52  
Old Sat Jun 4, 2011, 04:38 AM
suntime suntime is offline
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5 days ago I modified my dosage of LDN - meaning that I lowered it. The basic principle behind lowering the dosage is that we're talking about 'homeopathic' quantities. Thus, the less 'material' the more information, I thought.

Also, I read somewhere that a woman found out that she didn't make any use of the original - or widely recommended - dosage, which is 4.5mg. She tried 2.5 - 3.0mg and it worked a lot better for her (with her SM).

So 5 days have passed with my 'new' 3.0mg LDN. Something has definitely changed, as I sleep a lot better and have really vivid dreams - so vivid that I can't decide what is real.

I came in the hospital 2 days ago, the 5-week treatment has begun. I am hoping for the best... while being content with what I have

Blessings to All,
sun
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Gustav, 28 male; diagnosed SAA 27/12/2010.
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  #53  
Old Wed Jul 13, 2011, 07:42 AM
Marlene Marlene is offline
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New study on LDN...

and ovarian cancer.

http://www.sciencedaily.com/releases...0712143012.htm
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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  #54  
Old Wed Jul 13, 2011, 08:52 AM
Lbrown Lbrown is offline
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Interesting. I wonder what "nude mice" are? Also have to be careful about extrapolating mice studies to humans. My mother in law died of ovarian cancer less than 2 years ago. She was stage 4 when it was diagnosed and had no symptoms up until then. The chemo made sure the strong cancer cells survived.

Deb
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  #55  
Old Wed Jul 13, 2011, 09:25 AM
Marlene Marlene is offline
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I think nude mice are hairless. And yes, mice vs human is an issue. Not sure why they have to test it on mice though since it's in use in humans today.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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  #56  
Old Wed Jul 13, 2011, 09:29 AM
Lbrown Lbrown is offline
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It may not be ethical to test on people with ovarian cancer. What is the significance of nude mice I wonder? I'm gonna go look it up.

Deb
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  #57  
Old Wed Jul 13, 2011, 09:37 AM
Lbrown Lbrown is offline
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Couldn't find much out about nude mice so far, but have a look at this:

Strains Of Laboratory Mice More Varied Than Previously Thought
http://www.sciencedaily.com/releases...0730092539.htm

"if one is studying mouse strains for responses to particular drugs, you make assumptions that the strains have certain pedigrees. If they don't, what you are doing may not mean anything."

Wow.
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  #58  
Old Wed Jul 13, 2011, 10:29 AM
Marlene Marlene is offline
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And I just saw this Huffington Post re humanized mice for drug testing. Wild stuff.

http://www.huffingtonpost.com/2011/0..._n_896539.html
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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  #59  
Old Wed Jul 13, 2011, 10:35 AM
Lbrown Lbrown is offline
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Well, maybe it'll have some useful applications. But human and mice immune systems are quite different. By only looking at how the liver deals with drugs, they are being very narrow.
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