Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > AA
Register FAQ Search Today's Posts Mark Forums Read

AA Aplastic anemia

Reply
 
Thread Tools Search this Thread
  #1  
Old Sun Aug 19, 2012, 01:59 AM
julieluvsmarco julieluvsmarco is offline
Member
 
Join Date: Dec 2011
Location: downey ca United States
Posts: 5
1 year after ATG

hi im new to posting but ive been reading posts for about a year.my daughter marie was diagnosed 6/27/2011 with severe aplastic anemia she was treated with atg on 07/12/2011,She started with a 10% cellularity having weekly platelet transfusions an bi- weekly blood transfusions.she has been on cyclosphorine for about a year.The last bone marrow aspiration was done Feb 2012 and showed 60% cellularity.she has been transfusion free for 6 months on both lines of blood.her wbc are at 6.7 and will go up if she has a little flu or what not, her hemoglobin lingers at a 10.5 but its steady. her platlets are lingering in the 30's and have fallen down to 15 but will rise on their own.my question is how long into the atg do platlets rise significantly.Our hemotologist tells us that the platelets are the last line to come back to normality.She says that shes doing great and its a waiting game. Im happy she is responding but also slightly confused. i would appreciate any input thanks in advanced
__________________
JULIET,MOTHER OF MARIE AGE 7,DIAGNOSED AA JUNE 2011;TREATED WITH ATG 2011:CURRENTLY ON CYCLOSPHORINE
Reply With Quote
  #2  
Old Sun Aug 19, 2012, 06:37 AM
NLJabbari NLJabbari is offline
Member
 
Join Date: Aug 2006
Location: San Jose, California
Posts: 139
Hi Juliet! Well congratulations...it sure does seem that your daughter is recovering quite well.

Re: platelet count, well I have read of other cases familiar to your daughters. The platelets do seem to rise albeit slowly, but surely. I also just wanted to mention that platelets are not necessarily the last line to respond. I think that for a large majority this might be the case, but for a few others the platelets are the first line to respond. I only say this because that was what happened in my son's case. His Hgb was last to rise and is always first to drop too! I never quite understood why a few people experience this and others don't.

Anyway, hope this helps
__________________
06/2004 my son was dx with SAA at the age of 10. No sibling BM match. He underwent ATG (H)/CsA. Relapsed 05/12 & dx'ed w/PNH. Currently in wait/see mode for Solaris as he is asymptomatic...
Reply With Quote
  #3  
Old Mon Aug 20, 2012, 08:23 PM
Lisa V Lisa V is offline
Member
 
Join Date: Aug 2006
Location: Waimanalo, Hawaii
Posts: 401
Juliet, I agree it sounds as though your daughter is doing well. As Norma said, platelets are not always the last line to respond, but it seems they are often very slow to bounce back. What you have to remember is that AA is not a single homogeneous disease, but rather a group of syndromes that share a similar set of symptoms. So one person's pattern of response my differ from another's.

Ken's Plts never rose above the high 20s his first time around. He relapsed when the cyclosporine was tapered, and had his second ATG a year and a half after the first. He showed a better response the second time around, but still slow. Here are his Plt counts at annual intervals, starting with 1 year after ATG.

1 yr: 56
2 yrs: 73
3 yrs: 113
4 yrs: 117
5 yrs: 127
6 yrs: 140

So basically for him it took 6 years to reach normal range. We relaxed a little once it hit 50, and when he got to 100 it was cause for celebration! He's been on a maintenance dose of cyclo all this time to avoid another relapse. His WBCs are still on the low side, however, so your daughter is doing better in that respect.

Hope this helps.
__________________
-Lisa, husband Ken age 60 dx SAA 7/04, dx hypo MDS 1/06 w/finding of trisomy 8; 2 ATGs, partial remission, still using cyclosporine
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Response to ATG Leung AA 32 Mon Dec 22, 2014 08:13 PM
please share lymphocytes counts before ATG, day1 of ATG and after 1 month of ATG pvinod AA 16 Fri Dec 30, 2011 03:32 PM
Update - my husband 1 year after 2nd ATG paulaespada AA 3 Mon Jul 18, 2011 07:07 PM
Second ATG at age 69? flyguy AA 6 Fri Jun 25, 2010 12:25 AM
Good news 1 year after ATG paulaespada AA 2 Thu Jun 18, 2009 05:34 PM


All times are GMT -4. The time now is 02:58 PM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org