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Transfusions and Iron Overload Blood and platelet transfusions, iron testing and treatments

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Old Thu Jan 18, 2007, 02:52 PM
Marlene Marlene is online now
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Tendon problems

Has anyone experienced any problems with their tendons as a result of iron overload and/or the use of Exjade? John ruptured his quad tendon back in September and then about a month later another on his middle finger. The finger is minor but it makes me wonder if there's any connection. The only other drug I know of that can cause spontaneous tendon ruptures is cipro but it usually occurs while on the med or shortly after.

Marlene
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of January 2017, FE is 233, HGB 11.7, WBC 5.1/ANC 4.0, Plts 146K.
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Old Fri Jan 19, 2007, 12:31 AM
Wendy Beltrami Wendy Beltrami is offline
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Hi Marlene,
There's a very real connection between tendon ruptures and several different antibiotics (not just cipro) but I've never heard of any connection to iron overload or chelating meds. If you google "tendon rupture antibiotic" you will get a lot of hits.

Wendy/mom to Grant
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Old Mon Jan 22, 2007, 09:45 AM
Marlene Marlene is online now
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Hi Wendy.....yeah that entire class of drugs is on the "do not use" list for John unless he's in life threatening situation. He has peripheral neuropathies and when he was on the cipro last year, it made it worse for a while. I think Levaquin is the worst though and the docs seems to use it as a first line of defense instead of other older classes of drugs that have less adverse side effects and are just as effective.

Marlene
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of January 2017, FE is 233, HGB 11.7, WBC 5.1/ANC 4.0, Plts 146K.
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