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AA Aplastic anemia

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Old Tue Jun 27, 2017, 11:16 AM
disco3md disco3md is offline
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NIH Trial - Plt Count Level Feedback/Experience

My wife was is currently in 6 month trial @ NIH. She's starting taking both Eltrombopag & Cyclosporine , and was taken off Eltrombopag and now taking only Cyclosporine. She is entering 5 month of trial, concern is her platelet count has been dropping over the 4 months ( 138, 120,11 & 99 most recently). NIH does not seem concerned. She may have a cold or virus.
Question - Has anyone had similar experience ? Does platelet count drop near the end of the trial? Appreciate any feedback
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Old Wed Jun 28, 2017, 01:08 PM
jef dk jef dk is offline
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No responce to Eltrombopaq

Hi
I was initially treated with ATG plus Eltrombopag & Cyclosporine, but was taken of Eltrombopag because it gave kidney failure. It is not quite similar to what your wife has experienced, but I had no positive effect of Eltrombopag. My platelets were very low to a start and grew first after I was taken of Eltrombopag, and it has taken more than a year to get close to 100 x 10exp9
Kind regards Jef
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