Bone Marrow Results Question

[MikeE07]

Hello All,

Hoping someone can help me with this question:

In 2010, I was diagnosed with MDS (RAEB-2) with 19-20% blasts. Upon presentation, my bone marrow was characterized as hypercellular (approx. 61% cellularity). In 2013, a repeat bone marrow biopsy classified the bone marrow as normocellular (approx. 40% cellularity) with 25% blasts. While a bone marrow biopsy, in 2014, categorized the marrow as hypo cellular (approx 29% cellularity) with 40-50% blasts. What would cause an initially hyper cellular bone marrow to become hypo cellular? If relevant, the 2014 bone marrow biopsy was conducted during an active infection.

Thanks!

[amyangel]

Wow ! sorry to hear how many blasts you have in 2014 not tomention all the other years too ,

my daughter had her BMB done in Feb. you I thought the something she was so septic and had so many infection I thought hoe could you even get a good biopsy done ???

Her hematologist thought the something too, but yet she knew she knew it was still going to come back MDS and she repeated the BMB after my daughter wasn't septic anymore and it just didn't matter it still showed up MDS / ALPS with fibrosis

prayers to you

[katgio50]

I am very confused about the number of blasts that you mentioned. I thought that anything over 20% was considered acute myeloid leukemia. Am I missing something here?