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Transplants Bone marrow and stem cell transplantation

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Old Mon Mar 26, 2012, 07:39 PM
Janire Janire is offline
Join Date: Apr 2011
Posts: 19
Bone marrow trasplant vs CORD blood trasplant

What Are the differences between a Bmt and a CORD blood transplant in aplastic anemia?.
Is a CORD blood trasplant also succesful in aplastic anemia??
I dont have a bone marrow donor. My doctor said to me that with a CORD trasplant they cant give me guarantees but i know that there are hospitals that make CORD trasplants with godo results.
Please, help me!!
Janire, age 31, diagnosed AA september 2007; treated with ATG november 2007, no response; 2xATG april 2008, total remission..... RELAPSE and 3xATG in april 2011....now waiting for a response... not always easy. Http://anemiaaplasica.blogspot.com
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Old Mon Mar 26, 2012, 09:38 PM
Neil Cuadra Neil Cuadra is offline
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,469
Hi Janire. Bone marrow transplants, stem cell transplants (also called "PBSC" transplants), and cord blood transplants are basically the same process. You are given conditioning ahead of time to try to eliminate "bad" cells that made your immune system faulty. Then donated "good" cells are given to you with the hope that they will take over as your new, functional immune system.

Bone marrow transplants have been done for decades. Stem cell transplants and cord blood transplants have become more and more common over the last decade. Originally, cord blood transplants were given only to children or small-bodied adults, simply because there aren't many cells in cord blood. But then transplant specialists figured out how to use two cord blood units in one transplant so cord blood is now available to patients of all sizes.

For treatment centers in the U.S. you can get statistics from the National Marrow Donor Program on how many of each type of transplant they have performed and for what diseases.

No matter which type of transplant it is, nobody can give you a guarantee of success. They are all risky, but so is not treating a serious disease. Researchers continue to study the tradeoffs among the methods and they do find statistical differences among bone marrow, PBSC, and cord-blood transplants, but none of these methods is clearly better than the others in all cases. Instead of picking one method for all patients, doctors look at the available donors as well as other factors such as the degree of match, your age, and your overall health.

Continue to ask questions, here and when talking to doctors, and you'll learn more that can help you to help yourself. You are your best health advocate!
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