Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > AA
Register FAQ Search Today's Posts Mark Forums Read

AA Aplastic anemia

Reply
 
Thread Tools Search this Thread
  #1  
Old Tue Apr 21, 2015, 06:25 PM
Missy D. Missy D. is offline
Member
 
Join Date: Nov 2014
Posts: 12
Promacta an side effects to liver

I haven't posted in awhile and wanted to give an update and had a few questions. My dad was diagnosed with SAA in September last year. Not healthy enough for atg or bmt. Tried cyclosporine but didn't help and side effects were too much for my dad and kidney levels too high. Started promacta at the first of the year. Just started max dose, 150mg, today. Platelets have been 3000 and today were 6000. I was excited by that,but doc wasn't. Anyone else think this is good or am I just being too hopeful? They haven't been above 4000 since this all started in June 2014. My biggest question is that today his doc was hesitant for him to continue the promacta because his liver numbers have been been increasing the past couple of weeks. His ALT today was 121 and his AST was 53. What is considered too high? Anyone else have issues with liver levels? Doc said if they continue to go up with no improvement in his numbers then he wants to stop promacta in a month and go to supportive care only. My dad is also on Keppra for his seizure disorder and in February started exjade. Wasn't sure if these could effect liver levels also? Also curious on how long to give the promacta before u know its not working? He's been able to go to every other weak for his blood transfusions, which he also was able to do while on cyclosporine. His blood work today was Hgb 9.1, RBC 3.16, ANC .71, WBC 1.5 and platelets 6000. Thank you!
__________________
Missy, daughter of Jerry; diagnosed SAA September 2014; treating with cyclosporine
Reply With Quote
  #2  
Old Tue Apr 21, 2015, 10:34 PM
riccd2001 riccd2001 is offline
Member
 
Join Date: Aug 2010
Location: Burlington,Ontario,Canada
Posts: 186
Side effects to kidney function caused by Exjade...

As for all patients YMMV but with Exjade use you have to keep a close eye on kidney function (Creatinine & Estimated GFR). Keep a record so you can see any trends.
__________________
Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Cyclosporine side effects BobbyJD Drugs and Drug Treatments 5 Tue Jun 24, 2014 01:48 AM
Long Term Side Effects of Vidaza Jill2008 Drugs and Drug Treatments 6 Sun Jun 1, 2014 08:35 PM
Vidaza side effects: enlarged spleen veola Drugs and Drug Treatments 0 Sun Jul 17, 2011 01:54 AM
cyclosporine side effects SNichols Drugs and Drug Treatments 11 Wed Oct 20, 2010 01:43 PM
Results and side effects from Vidaza Zita Desenberg Drugs and Drug Treatments 2 Mon Nov 16, 2009 05:41 PM


All times are GMT -4. The time now is 12:25 PM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2021, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright 2006-2020 Marrowforums.org